GHK-Cu
GHK-Cu is a naturally occurring tripeptide-copper complex, originally isolated from human plasma. Circulating levels decline with age—from ~200 ng/ mL at age 20 to ~80 ng/mL by age 60— correlating with decreased regenerative capacity. Mechanistically, GHK-Cu exerts its effects via dual pathways: Copper binding and metabolism: Transfers copper into/out of cells, essential for enzymatic and antioxidant activity. Gene modulation: Influences over 4,000 genes, generally restoring gene expression toward healthier, more youthful patterns. It stimulates collagen, elastin, glycosaminoglycan, and decorin synthesis, attracts immune and endothelial cells to injury sites, accelerates wound healing across tissues, and enhances repair in radiation-damaged fibroblasts.
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